If the player has killed innocents on any stage, they will either maintain their rank or will be demoted. When the game begins, the player's rank is Sheriff, and after each stage the player will be promoted, provided they have not killed any innocents. The ranks are: Posse, Deputy, Sheriff, Deputy Marshal and U.S. There are different ranks that the player can attain, depending on how well the player performs. If a player is shot with one of those weapons, the weapon is lost and the player will return to the regular gun. The gatling guns and cannons can each be used only once but the other four weapons can be reloaded the same way as the regular gun. Additional weaponry can be found throughout the game that will give the player better firepower: 50 calibre sharps, rifles, double rigs, shotguns, gatling guns, and cannons. To reload, the player must aim his or her lightgun away from the screen and pull the trigger. In the game, the player's gun (a six-shooter) can carry up to six bullets. One shot is usually enough to kill most enemies. If the player does hit a townsfolk, the game will issue and admonishment like 'Don't shoot innocent folks!'. Lethal Enforcers 2 has five stages: 'The Bank Robbery,' 'The Stage-Holdup,' 'Saloon Showdown,' 'The Train Robbery,' and 'The Hide-Out.' During each stage, the player must shoot the armed outlaws without harming any innocent townsfolk or fellow lawmen. The game ends when all life units are gone, but continue play is available. Every time the player is shot or an innocent townsperson or lawmen is shot, one life unit will be lost. Life units are also awarded based on how many points the player scores while playing the game. In the arcade version, more can be purchased by inserting additional coins. At the beginning of the game, three to five life units are available.

The object in the game is to shoot outlaws in order to eradicate crime from a stereotypical Old West town.

The SNES port was supposed to come but never was released. It was later ported to the Sega Genesis and Sega CD. Lethal Enforcers II: Gun Fighters was a first person shooter made by Konami for the arcade.

Lethal enforcers snes gun